个人简介/Profile
博士生导师，生物化学与分子生物学系主任，四川省生物化学与分子生物学学会理事。先后主持主研国家级和省级科研课题十余项，参与获得省级科技进步奖一等奖2项，三等奖1项，发表论文50余篇，其中SCI收录30余篇。现主要从事植物次生代谢调控及抗逆分子机制研究，在苦荞黄酮合成代谢酶学机理研究及转录因子分子调控、苦荞抗逆相关转录因子调控机制研究在领域内处于领先水平。
Engaged in advanced research focused on the identification and characterization of regulatory genes and networks responsible for the development of quality traits in Tartary buckwheat, deciphering the genetic mechanisms underlying Tartary buckwheat's resilience to environmental stresses, and conducting comprehensive biological assessments of its functional components.
研究方向/Research Interests
植物次生代谢调控及抗逆分子机制研究
Metabolism regulation & stress biology in plant
研究内容/Research Contents
苦荞黄酮合成代谢酶学机理研究及转录因子分子调控、苦荞抗逆相关转录因子调控机制研究在领域内处于领先水平。
1. Molecular mechanisms of starch and flavonoid biosynthesis in Tartary buckwheat.
2. Regulatory mechanisms of drought tolerance in Tartary buckwheat.
招生专业/Enrollment Major
【博士】071010生物化学与分子生物学
【学硕】071010生物化学与分子生物学
【专硕】086000生物与医药
Email：wuqi@sicau.edu.cn
【Doctoral】:071010 Biochemistry and molecular biology
【Academic Master】:071010 Biochemistry and molecular biology
【Professional Master】:086000 Biology and Medicine
教育背景/Education
2013-2014，美国普渡大学，访问学者
2001-2004，四川大学，理学博士
1997-2000，四川农业大学，农学硕士
1991-1995，四川畜牧兽医学院，农学学士
1991-1995，Sichuan Institute of Animal Husbandry and Veterinary Medicine, Veterinary Medicine，B.S
1997-2000，Sichuan Agricultural University, Preventive Veterinary Medicine, M.S
2001-2004，Sichuan University, Genetics, Ph.D
工作经历/Working Experience (Full-time)
2012年至今，四川农业大学生命科学学院，教授
2006年至2012年，四川农业大学生命科学与理学院，副教授
2004年至2006年，四川农业大学生命科学与理学院，讲师
2004-2006, Sichuan Agricultural University, College of Life and Basic Sciences, Lecturer
2006-2012, Sichuan Agricultural University, College of Life and Basic Sciences, Associate Professor
2012 to date, Sichuan Agricultural University, College of Life Science, Professor
主要社会兼职/Social Part-time
四川省生物化学与分子生物学学会理事
中国作物学会燕麦荞麦专业委员会理事
2023 to date, Council Member of the Sichuan Provincial Biochemistry and Molecular Biology Society
2023 to date,Council Member of Oat and Buckwheat Committee of the Chinese Society of Crop Science
主要科研奖励和个人荣誉/Awards and Honors
获四川省科技进步一等奖2项、三等奖1项
2014, Third-Class Prize for Scientific and Technological Progress in Sichuan Province
代表性科研项目/Representative Projects
1.四川省科技厅国际合作项目，2014HH0012，苦荞米荞一号易脱壳性状的差异蛋白质组研究，2014/01-2015/12，30万元，主研
2.国家自然科学基金青年科学基金项目，31500289，苦荞黄酮醇合酶FLS同源基因的分子克隆、催化特征及其对芦丁合成的影响，2016/01-2018/12，20万元，主研
3.四川省科技厅国际合作项目，14GH0098，苦荞黄酮合成相关MYB转录因子基因资源的挖掘与利用，2015/01-2016/12，30万元，主持
4.国家自然科学基金面上项目，31871699，苦荞转录因子FtMYB22的抗逆分子机制研究，2019/01-2022/12，60万元，主持
5.西南作物基因资源发掘与利用国家重点实验室开放课题（重点），SKL-KF202211，苦荞自噬相关基因FtATG8f在干旱胁迫应答中的功能研究, 2022/09-2024/08，10万元，主持
6.攀西特色作物研究与利用四川省重点实验室开放基金项目, SZKF2205, 苦荞响应低磷胁迫WRKY转录因子的基因挖掘与功能解析, 2022/07-2024/06, 10万元, 主持
1. Investigation of the Molecular Mechanisms of a Transcription Factor FtMYB22 Resistant to Stress in Tartary Buckwheat, the National Natural Science Foundation of China, 2019-2022.
2. Development, Selective Breeding, and Agronomic Trait Analysis of High-Yield, High-Density Tolerant Tartary Buckwheat Germplasms, a Regional Innovation Cooperation Project funded by the Sichuan Provincial Department of Science and Technology, 2024-2025.
代表性学术成果/Representative Publications
1.Haixia Zhao#, Xin Li#, Xin Xiao#, Tao Wang, Lisong Liu, Chenglei Li, Huala Wu, Zhi Shan, Qi Wu *.Evaluating Tartary buckwheat genotypes with high callus induction rates and the transcriptomic profiling during callus formation. Plants, 2023,12,3663
2.Lei Wang#, Linling Liu#, Jiali Zhao, Chenglei Li, Huala Wu, Haixia Zhao, Qi Wu*. Granule-bound starch synthase in plants: Towards an understanding of their evolution, regulatory mechanisms, applications, and perspectives. Plant Science, 2023, 336, 111843
3.Lei Wang, Linling Liu, Huala Wu, Chenglei Li, Haixia Zhao, Qi Wu*.Evolutionary and expression analysis of starch synthase genes from Tartary buckwheat revealed the potential function of FtGBSSII-4 and FtGBSSII-5 in seed amylose biosynthesis. Crop Science, 2023
4.Guohui Nan#, Haixia Zhaoa#, Qiong Wua, Lisong Liua, Zichao Guana, Chenglei Lia, Huala Wua, Dabing Xiangc, Qi Wu*.Comparative Study of the Effects of Tartary Buckwheat Seed and Sprout Consumption on the Physiological Indices and Gut Microbiota of C57BL/6J Mice. Food Science and Human Wellness, 2023
5.Yue Fang#, Shuang Wang#, Hula Wu, Chenglei Li, Haixia Zhao, Hui Chen, Xiaoli Wang*, Qi Wu*. Genome-wide identification of ATG gene family members in Fagopyrum tataricum and their expression during stress responses. Int J Mol Sci, 2022, 23: 14845.
6.Haixia Zhao#,Panfeng Yao#, Jiali Zhao, Huala Wu, Shuang Wang, Ying Chen, Mufan Hu, Tao Wang, Chenglei Li, Qi Wu*. A novel R2R3-MYB transcription factor FtMYB22 negatively regulates salt and drought stress through ABA-dependent pathway. Int J Mol Sci, 2022, 23: 14549
7.Guohui Nan#, Lisong Liu#, Huala Wu, Shiyuan Yin, Chenglei Li, Haixia Zhao, Hui Chen, Qi Wu*. Transcriptomic and Metabonomic Profiling Reveals the Antihyperlipidemic Effects of Tartary Buckwheat Sprouts in High-Fat-Diet-Fed Mice. J Agric Food Chem. 2022, 70(41): 13302-13312.
8.Jiali Zhao#, Qiong Wu#, Huala Wu, Anhu Wang, Xiaoli Wang 5, Chenglei Li 6, Haixia Zhao, Qi Wu*. FtNAC31, a Tartary buckwheat NAC transcription factor, enhances salt and drought tolerance in transgenic Arabidopsis. Plant Physiology and Biochemistry, 2022, 191: 20-33
9.Shuang Wang, Huala Wu, Xinxian Cao, Wenjing Fan, Chenglei Li, Haixia Zhao, Qi Wu*.Tartary buckwheat FtMYB30 transcription factor improves the salt/drought tolerance of transgenic Arabidopsis in an ABA-dependent manner. Physiologia Plantarum. 2022,174: e13781
10.赵海霞，肖欣，董玘鑫，吴花拉，李成磊，吴琦*.苦荞愈伤遗传转化体系的优化及用于 FtCHS1 的过表达分析.中国农业科学, 2022, 55(9): 1723-1734
11.Guohui Nan, Huala Wu, Qiong Wu, Lisong Liu, Qiancheng Liao, Chenglei Li, Hui Chen, Qi Wu*. Cloning, identification, and functional analysis of chalcone isomerase gene and its promoter from Tartary buckwheat. Acta Physiol Plant, 2022, 44(8): 78
12.Yingjun Yao#, Haixia Zhao#, Lei Sun, Wenjing Wu, Chenglei Li, Qi Wu*. Genome-wide identifcation of MAPK gene family members in Fagopyrum tataricum and their expression during development and stress responses. BMC Genomics, 2022,23:96
13.Hongyou Li#*, Qiuyu Lv#, Ake Liu, Jiarui Wang, Xiaoqian Sun, Jiao Deng, Qingfu Chen*, Qi Wu*. Comparative metabolomics study of Tartary (Fagopyrum tataricum (L.) Gaertn) and common (Fagopyrum esculentum Moench) buckwheat seeds. Food Chemistry,2021: 131125
14.Yingjun Yao#, Lei Sun#, WenJing Wu, Shuang Wang, Xin Xiao, MinLun Hu, ChengLei Li, HaiXia Zhao, Hui Chen, Qi Wu*. Genome-wide investigation of major enzyme encoding genes in the flavonoid metabolic pathway in Tartary buckwheat (Fagopyrum tataricum).Journal of Molecular Evolution, 2021, 89:269–286
15.Qixin Dong#, Haixia Zhao#, Yunji Huang, Ying Chen, Min Wan, Zixian Zeng, Panfeng Yao, Chenglei Li, Xiaoli Wang, Hui Chen, Qi Wu*. FtMYB18 acts as a negative regulator of anthocyanin/proanthocyanidin biosynthesis in Tartary buckwheat. Plant Molecular Biology, 2020, 104(3):309-325
16.Bingbing Lv#, Qi Wu#, Anhu Wang, Qi Li, Qixin Dong, Jingjing Yang, Haixia Zhao, Xiaoli Wang, Hui Chen, Chenglei Li*. A WRKY transcription factor, FtWRKY46, from Tartary buckwheat improves salt tolerance in transgenic Arabidopsis thaliana. Plant Physiology and Biochemistry, 2020, 147: 43-53
17.Qi Li#, Qi Wu#, Anhu Wang, Bingbing Lv, Qixin Dong, Yingjun Yao, Qiong Wu, Haixia Zhao, Chenglei Li, Hui Chen, Xiaoli Wang*.Tartary buckwheat transcription factor FtbZIP83 improves the drought/salt tolerance of Arabidopsis via an ABA-mediated pathway. Plant Physiology and Biochemistry, 2019, 144: 312-323
18.Yunji Huang#, Qi Wu#, Shuang Wang, Jiaqi Shi, Qixin Dong, Panfeng Yao, Guannan Shi, Shuangxiu Xu, Renyu Deng, Chenglei Li, Hui Chen, Haixia Zhao*. FtMYB8 from Tartary buckwheat inhibits both anthocyanin/Proanthocyanidin accumulation and marginal Trichome initiation. BMC Plant Biology, 2019,19:263
19.Chenglei Li, Haixia Zhao, Maofei Li, Panfeng Yao, Qingqing Li, Xuerong Zhao, Anhu Wang, Hui Chen, Zizhong Tang, Tongliang Bu, Qi Wu*. Validation of reference genes for gene expression studies in tartary buckwheat (Fagopyrum tataricum Gaertn.) using quantitative real-time PCR. Peer J, 2019, 7:e6522
20.Renyu Deng, Haixia Zhao, Yuhua Xiao, Yunji Huang, Panfeng Yao, Yunlong Lei, Chenglei Li, Hui Chen, Qi Wu*. Cloning, Characterization, and Expression Analysis of Eight Stress-Related NAC Genes in Tartary Buckwheat. Crop Science, 2019, 59(1): 266-279.
21.Yunji Huang#, Haixia Zhao#, Fei Gao, Panfeng Yao, Renyu Deng, Chenglei Li, Hui Chen, Qi Wu*. A R2R3-MYB transcription factor gene, FtMYB13, from Tartary buckwheat improves salt/drought tolerance in Arabidopsis. Plant Physiology and Biochemistry, 2018, 132: 238–248.
22.Panfeng Yao, Zhaoxia Sun, Chenglei Li, Xuerong Zhao, Maofei Li, Renyu Deng, Yunji Huang, Haixia Zhao, Hui Chen, Qi Wu*. Overexpression of Fagopyrum tataricum FtbHLH2 enhances tolerance to cold stress in transgenic Arabidopsis[J]. Plant Physiol Biochem, 2018, 125: 85-94.
23.Xiaopeng Luo, Haixia Zhao, Panfeng Yao, Qingqing Li, Yunji Huang, Chenglei Li, Hui Chen, Qi Wu*. An R2R3-MYB Transcription Factor FtMYB15 Involved in the Synthesis of Anthocyanin and Proanthocyanidins from Tartary Buckwheat. [J]. Journal of Plant Growth Regulation, 2018, 37(1): 76-84.
24.Yunlong Lei, Peipei Zhao, Chenglei Li, Haixia Zhao, Zhi Shan, Qi Wu*. Isolation, identification and characterization of a novel elastase from Chryseobacterium indologenes[J]. Applied Biological Chemistry, 2018, 61(3): 365-372.
25.Panfeng Yao, Chenglei Li, Xuerong Zhao, Maofei Li, Haixia Zhao, Jinya Guo, Yi Cai, Hui Chen, Qi Wu*. Overexpression of a Tartary Buckwheat Gene,FtbHLH3, Enhances Drought/Oxidative Stress Tolerance in Transgenic Arabidopsis:[J]. Front Plant Sci, 2017, 8:625.
26.Fei Gao, Jing Zhou, Ren-Yu Deng, Hai-Xia Zhao, Cheng-Lei Li, Hui Chen, Tatsuro Suzuki, Sang-Un Park, Qi Wu*. Overexpression of a tartary buckwheat R2R3-MYB transcription factor gene, FtMYB9, enhances tolerance to drought and salt stresses in transgenic Arabidopsis. Journal of Plant Physiology. 2017, 214: 81–90
27.Huipeng Yao, Chenglei Li, Haixia Zhao, Jianlan Zhao, Hui Chen, Tongliang Bu, Wang Anhu, Qi Wu*. Deep sequencing of the transcriptome reveals distinct flavonoid metabolism features of black tartary buckwheat (Fagopyrum tataricum Garetn.). Progress in Biophysics and Molecular Biology. 2017, 124: 49-60
28.Jing Zhou, Chenglei Li, Fei Gao, Xiaopeng Luo, Qingqing Li, Haixia Zhao, Huipeng Yao, Hui Chen, Anhu Wang, Qi Wu*. Characterization of Three Glucosyltransferase Genes in Tartary Buckwheat and Their Expression after Cold Stress. J. Agric. Food,2016,64:6930-6938
29.Panfeng Yao, Haixia Zhao, Xiaopeng Luo, Fei Gao, Chenglei Li, Huipeng Yao, Hui Chen, SangUn Park, Qi Wu*. Fagopyrum tataricum FtWD40 Functions as a Positive Regulator of Anthocyanin Biosynthesis in Transgenic Tobacco. Journal of Plant Growth Regulation, 2017, 36(3):755-765
30.Fei Gao, Haixia Zhao, Huipeng Yao, Chenglei Li, Hui Chen, Anhu Wang, Sangun Park, Qi Wu*. Identification, isolation and expression analysis of eight stressrelated R2R3-MYB genes in tartary buckwheat (Fagopyrum tataricum). Plant Cell Rep, 2016, 35(6): 1385–1396
31.Fei Gao, Hui-Peng Yao, Hai-Xia Zhao, Jing Zhou, Xiao-Peng Luo, Yun-Ji Huang, Cheng-Lei Li, Hui Chen, Qi Wu*. Tartary buckwheat FtMYB10 encodes an R2R3-MYB transcription factor that acts as a novel negative regulator of salt and drought response in transgenic Arabidopsis. Plant Physiology and Biochemistry, 2016, 109: 387-396.
32.Xiaopeng Luo, Haixia Zhao, Jun Xue, Chenglei Li, Hui Chen, Sangun Park, Qi Wu*. Cloning of two basic helix-loop-helix transcription factor genes from Tartary buckwheat (Fagopyrum tataricum) and their expression under abiotic stress. Turk J Biol, 2016, 40: 1192-1201.
33.Panfeng Yao, Haixia Zhao, Xiaopeng Luo, Fei Gao, Huipeng Yao, Hui Chen, Qi Wu*. Chalcone Synthase Homologous Genes Cloning and Expression Pattern in Flowering Fagopyrum tataricum Gaertn. Russian Journal of Plant Physiology, 2016, 63(6): 790–799.
34.Shuangjiang Li, Yuechen Bai, Chenglei Li, Huipeng Yao, Hui Chen, Haixia Zhao, Qi Wu*. Anthocyanins accumulate in tartary buckwheat (Fagopyrum tataricum) sprout in response to cold stress. [J]. Acta Physiologiae Plantarum, 2015, 37(8):1-8.
35.Yuechen Bai, Chenglei Li, Jinwen Zhang, Shuangjiang Li, Xiaopeng Luo, Huipeng Yao, Hui Chen, Haixia Zhao, Sangun Park, Qi Wu*. Characterization of two tartary buckwheat R2R3-MYB transcription factors and their regulation of proanthocyanidin biosynthesis. Physiologia Plantarum. 2014: 431–440.
36.Xiaowei Zhang, Chenglei Li, Qiantao Jiang, Yuming Wei, Huipeng Yao, Hui Chen, Qi Wu*. Cloning and characterization of a cold inducible Pal promoter from Fagopyrum tataricum. Cent. Eur. J. Biol. 2014, 9(3): 290-297.
37.Chenglei Li, Yuechen Bai, Shuangjiang Li, Hui Chen, Xueyi Han, Haixia Zhao, Jirong Shao,Sang-un Park, Qi Wu*. Cloning, Characterization, and Activity Analysis of a Flavonol Synthase Gene FtFLS1 and Its Association with Flavonoid Content in in Tartary Buckwheat. J. Agric. Food,2012,60:5161-5168
38.Chenglei Li, Yuechen Bai, Hui Chen, Haixia Zhao, Jirong Shao, Qi Wu*. Cloning, Characterization and Functional Analysis of a Phenylalanine Ammonia-lyase Gene (FtPAL) from Fagopyrum tataricum Gaertn. Plant Molecular Biology Reporter. [J]. Plant Molecular Biology Reporter, 2012, 30(5):1172-1182.
科研团队简介/Research Group
课题组名称：荞麦代谢调控与逆境生物学
课题组负责人：吴琦教授
课题组成员：陈惠教授、王晓丽教授、单志教授、赵海霞副教授、李成磊讲师、吴花拉讲师
课题组在读博士生：王磊、王霜、赵佳利、张蓥杰
课题组在读硕士生：李力、胡沐凡、刘琳玲、唐瑜、李辉、马琪涵、李鑫、谢雪梅、刘李松、张畅、周姝延、毛远彬、曾道萍、徐卿、欧阳宇峻、侯可之、吴健
Our research group consists of four professors, two associate professors, and three lecturers. We have meticulously collected over twenty wild and related buckwheat species from the southwestern regions of China, leading to the identification of six new species within the buckwheat genus. Our team has made notable advances in elucidating the genetic mechanisms and regulatory networks involved in flavonoid synthesis, starch synthesis, and dehulling traits. Additionally, we have contributed significant insights into the physiological and biochemical mechanisms underlying the stress resistance of tartary buckwheat. These accomplishments have established a strong presence in both national and international circles. This year, we have been responsible for three national key R&D project topics, managed four projects funded by the National Natural Science Foundation of China, and led over ten provincial-level research initiatives.
教学情况/Teaching Courses
主讲硕士生《分子生物学及实验技术》
主讲博士生《生物化学与分子生物学前沿》
1. Molecular Biology, General Biochemistry（Undergraduate）
2. Experiment technology of Molecular Biology (Postgraduate）
3. Frontier in Biochemistry & Molecular Biology（Postgraduate）
