个人简介
本人从事植物分子生物学的研究,现主要研究领域为苦荞黄酮生物合成相关基因的克隆及其调控。主持国家自然科学基金面上项目2项、四川省自然科学基金面上项目1项,主研国家级、省级课题多项,发表论文20篇。
研究方向
植物次生代谢调控及抗逆分子机制研究
研究内容
苦荞黄酮合成相关转录因子基因的挖掘与利用
招生专业
【学硕】071010生物化学与分子生物学
【专硕】086000生物与医药
Email:zhaohaixia@sicau.edu.cn
教育背景
2001.9–2004.6,四川农业大学,理学硕士
1997.9–2001.6,辽宁师范大学,理学学士
工作经历
2013.2-至今,四川农业大学,生命科学学院,副教授
2007.12-2013.1,四川农业大学,生命科学与理学院,助理研究员
2004.12-2007.11,四川农业大学,生命科学与理学院,研究实习员
主要社会兼职
中国作物学会燕麦荞麦专业委员会会员
代表性科研项目
7.国家自然科学基金面上项目,32372032,光响应模块“FtmiRNA858a-FtBTB-FtMYB6”协同调控苦荞芦丁合成的分子机理,2024/01-2027/12,主持
6.四川省自然科学基金面上项目,23NSFSC0608,苦荞芦丁含量关联基因FtUFGT163优异单倍型的挖掘与鉴定,2023/01-2024/12,主持
5.国家自然科学基金面上项目,31871698,苦荞转录因子FtMYB5和FtMYB6特异性调控黄酮醇合成的分子机制,2019/01-2022/12,主持
4.国家自然科学基金青年科学基金项目,31500289,苦荞黄酮醇合酶FLS同源基因的分子克隆、催化特征及其对芦丁合成的影响,2016/01-2018/12,主研
3.四川省科技厅国际合作项目,14GH0098,苦荞黄酮合成相关MYB转录因子基因资源的挖掘与利用,2015/01-2016/12,主研
2.四川省科技厅国际合作项目,2014HH0012,苦荞米荞一号易脱壳性状的差异蛋白质组研究,2014/01-2015/12,主研
1.四川省教育厅青年基金项目,14ZB0008,黑苦荞和黄苦荞花期总黄酮含量与相关基因表达量的对比研究,2014/01-2016/12,主研
代表性学术成果
(21) Haixia Zhao#, Xin Li#, Xin Xiao#, Tao Wang, Lisong Liu, Chenglei Li, Huala Wu, Zhi Shan, Qi Wu *.Evaluating Tartary buckwheat genotypes with high callus induction rates and the transcriptomic profiling during callus formation. Plants, 2023,12,3663
(20) Haixia Zhao#, Panfeng Yao#, Jiali Zhao, Hula Wu, Shuang Wang, Ying Chen, Mufan Hu, Tao Wang, Chenglei Li, Qi Wu*. FtMYB22, an R2R3-MYB transcription factor from Tartary buckwheat, negatively regulates salt and drought stress through ABA-dependent pathway. Int J Mol Sci. 2022,23: 14549
(19) Chenglei Li#, Jingjing Yang#, Kai Yang#, Huala Wu, Hui Chen, Qi Wu, Haixia Zhao*. Tartary buckwheat FtF3′H1 as a metabolic branch switch to increase anthocyanin content in transgenic plant. Front. Plant Sci. 2022,13:1056857
(18) 赵海霞,肖欣,董玘鑫,吴花拉,李成磊,吴琦*. 苦荞愈伤遗传转化体系的优化及用于FtCHS1 的过表达分析. 中国农业科学 2022,55(9):1723-1734
(17) Lei Wang#, Renyu Deng#, Yuechen Bai, Huala Wu, Chenglei Li, Qi Wu, Haixia Zhao*. Tartary buckwheat R2R3-MYB gene FtMYB3 negatively regulates anthocyanin and proanthocyanin biosynthesis.Int J Mol Sci. 2022, 23: 2775
(16)Panfeng Yao#, Yunji Huang#, Qixin Dong#, Min Wan, Anhu Wang, Yuwei Chen, Chenglei Li, Qi Wu, Hui Chen, and Haixia Zhao*. FtMYB6, a light-induced SG7 R2R3-MYB transcription factor, promotes flavonol biosynthesis in Tartary buckwheat (Fagopyrum tataricum). Journal of Agricultural and Food Chemistry, 2020, 68(47): 13685–13696
(15) Qixin Dong#, Haixia Zhao#, Yunji Huang, Ying Chen, Min Wan, Zixian Zeng, Panfeng Yao, Chenglei Li, Xiaoli Wang, Hui Chen, Qi Wu*. FtMYB18 acts as a negative regulator of anthocyanin/proanthocyanidin biosynthesis in Tartary buckwheat. Plant Molecular Biology, 2020,104: 309–325
(14) Qi Li#, Haixia Zhao#, Xiaoli Wang, Jingyue Kang, Bingbing Lv, Qixin Dong, Chenglei Li, Hui Chen, Qi Wu*.Tartary buckwheat transcription factor FtbZIP5, regulated by FtSnRK2.6, can improve salt/drought resistance in transgenic arabidopsis. International Journal of Molecular Sciences, 2020, 21, 1123: 1-16
(13) Panfeng Yao, Renyu Deng, Yunji Huang, Simon Stael, Jiaqi Shi, Guanlan Shi, Bingbing Lv, Qi Li, Qixin Dong, Qi Wu, Chenglei Li, Hui Chen, Haixia Zhao*. Diverse biological effects of glycosyltransferase genes from Tartary buckwheat. BMC Plant Biology, 2019, 19: 339
(12) Yunji Huang#, Qi Wu#, Shuang Wang, Jiaqi Shi, Qixin Dong, Panfeng Yao, Guannan Shi, Shuangxiu Xu, Renyu Deng, Chenglei Li, Hui Chen, Haixia Zhao*. FtMYB8 from Tartary buckwheat inhibits both anthocyanin/Proanthocyanidin accumulation and marginal Trichome initiation. BMC Plant Biology, 2019,19:263
(11) Yunji Huang#, Haixia Zhao#, Fei Gao, Panfeng Yao, Renyu Deng, Chenglei Li, Hui Chen, Qi Wu*. A R2R3-MYB transcription factor gene, FtMYB13, from Tartary buckwheat improves salt/drought tolerance in Arabidopsis. Plant Physiology and Biochemistry, 2018, 132: 238–248.
(10) Luo, Xiaopeng; Zhao, Haixia; Yao, Panfeng; Li, Qingqing; Huang, Yunji; Li, Chenglei; Chen, Hui; Wu, Qi*. An R2R3-MYB transcription factor FtMYB15 involved in the synthesis of anthocyanin and proanthocyanidins from tartary buckwheat, Journal of Plant Growth Regulation, 2018, 37(1): 76-84.
(9) Luo, Xiao-Peng ; Li, Shuang-Jiang ; Yao, Pan-Feng; Li, Cheng-Lei; Chen, Hui; Wu, Qi; Zhao, Hai-Xia*. The jasmonate-ZIM domain protein FtJAZ2 interacts with the R2R3-MYB transcription factor FtMYB3 to affect anthocyanin biosynthesis in tartary buckwheat , Turkish Journal of Biology, 2017, 41(3): 526-534.
(8) Yao, Panfeng; Zhao, Haixia; Luo, Xiaopeng; Gao, Fei; Li, Chenglei; Yao, Huipeng; Chen, Hui; Park, Sang-Un; Wu, Qi*. Fagopyrum tataricum FtWD40 functions as a positive regulator of anthocyanin biosynthesis in transgenic tobacco , Journal of Plant Growth Regulation, 2017, 36(3): 755-765.
(7) Yao, Huipeng; Li, Chenglei; Zhao, Haixia; Zhao, Jianlan; Chen, Hui; Bu, Tongliang; Anhu, Wang; Wu, Qi*. Deep sequencing of the transcriptome reveals distinct flavonoid metabolism features of black tartary buckwheat (Fagopyrum tataricum Garetn.) , Progress in Biophysics & Molecular Biology, 2017, 124: 49-60.
(6) Luo, Xiao-Peng#; Zhao, Hai-Xia #; Xue, Jun; Li, Cheng-Lei; Chen, Hui; Park, Sang-Un; Wu, Qi*. Cloning of two basic helix-loop-helix transcription factor genes from Tartary buckwheat (Fagopyrum tataricum) and their expression under abiotic , Turkish Journal of Biology, 2016, 40(6): 1192-1201.
(5) Yao, Panfeng; Zhao, Haixia; Luo, Xiaopeng; Gao, Fei; Yao, Huipeng; Li, Chenglei; Chen, Hui; Wu, Qi*. Chalcone synthase homologous genes cloning and expression pattern in flowering Fagopyrum tataricum Gaertn , Russian Journal of Plant Physiology, 2016, 63(6): 790-799.
(4) 赵经昊; 李成磊; 姚慧鹏; 陈惠; 赵海霞*; 吴琦. 苦荞黄酮转运相关蛋白基因FtAH4L的克隆及表达分析, 西北植物学报, 2015, 35(8): 1511-1517.
(3) 高飞; 周婧; 刘晓彤; 李成磊; 姚慧鹏; 赵海霞*; 吴琦. 苦荞锌指蛋白基因FtLOL1的克隆及其对非生物胁迫的应答, 中国生物工程杂志, 2015, 35(8): 44-50.
(2) 赵海霞*; 李双江; 李成磊; 陈惠; 吴琦. 苦荞谷胱甘肽转移酶(FtGST)基因的克隆与序列分析 , 生物技术通报, 2012, (7): 70-76.
(1) 赵海霞; 吴小峰; 白悦辰; 李成磊; 陈惠; 邵继荣; 吴琦*. 苦荞芽期黄酮合成关键酶和MYB转录因子基因的表达分析 , 农业生物技术学报, 2012, 20(2): 121-128.
科研团队简介
课题组名称:荞麦代谢调控与逆境生物学
课题组负责人:吴琦教授
课题组成员:陈惠教授、王晓丽教授、单志教授、赵海霞副教授、李成磊讲师、吴花拉讲师